Replicability of Differentially Expressed Genes Versus Biological Pathways Biomarkers in Diagnosing Sepsis.
Published in Bioinformatics, 2022
In this work, we evaluated if pathway based signatures are really more reproducible than gene signatures (improvement between 0.83 and over 1 million fold), and amend a meta-analysis framework known for generating highly reproducible gene signatures to instead produce pathway signatures (AUC improves from 0.854 to 0.964 and 0.556 to 0.677 between gene and pathway signatures in independent validation data).
Recommended citation: Your Name, You. (2010). "Paper Title Number 2." Journal 1. 1(2). http://academicpages.github.io/files/paper2.pdf